Lithium ototoxicity
WebCisplatin-induced early-onset ototoxicity is linked to hearing loss. The mechanism by which cisplatin causes ototoxicity remains unclear. The purpose of this study was to identify the involvement of receptor-interacting protein kinase (RIP)3-dependent necroptosis in cisplatin-induced ototoxicity in vitro and in vivo. Sprague–Dawley rats (SD, 8 week) were treated … Web17 mrt. 2024 · Ototoxicity Review: A Growing Number of Non-Platinum-Based Chemo- and Immunotherapies. James G Naples, Wyatt Rice-Narusch, Nathan W Watson, Melissa Ghulam-Smith, Sean Holmes, Daqing Li,...
Lithium ototoxicity
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Web1 jan. 2015 · Een lithiumintoxicatie is een ernstige en potentieel levensbedreigende toestand waarbij onmiddellijk ingrijpen noodzakelijk is. Een acute intoxicatie kan het gevolg zijn van een eenmalige inname van een hoge dosis bij een lithiumnaïeve patiënt, of een auto-intoxicatie (tentamen suicidii) bij een patiënt die lithium gebruikt. WebSome studies have suggested that taking lithium in the first trimester is associated with a small increased chance of heart defects, especially a rare heart defect called …
Web1 jan. 2015 · Lithium has been widely used in the management of various psychiatric disorders. There are many known side effects of lithium and there therapeutic drug … WebLithium (Li) is the lightest metal and occurs primarily in stable minerals and salts. Concentrations of Li in surface water are typically <0.04 mg l−1 but can be elevated in …
WebDeletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity . Genetics ... Xiaochang Zhao, Heidi J. Henderson, Tianying Wang, Bo Liu, Yi Li. WebS1P2 may serve as a therapeutic target for attenuating cisplatin-mediated ototoxicity. JTE-013 is a known specific S1P2 antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to membranes of Chinese hamster ovary cells transfected with human and rat S1P2, with IC 50 values of 17 nM and 22 nM.
WebLithium is a small, positively charged ion. Narrow therapeutic index (0.8-1.2 mEq/L); many patients on lithium for long periods of time will endure a toxic event at least once during …
Web26 jan. 2024 · National Center for Biotechnology Information song- once was a ship put to seaWebDrug Ototoxicity Ototoxic drugs Drug classes most associated with ototoxicity include antibiotics, such as aminoglycosides, gly-copeptides and macrolides11-16; platinum-based an-titumor drugs5,17-20; loop diuretics, such as furose-mide21,22; antimalarial drugs, such as quinine and chloroquine23,24; nonsteroidal anti-inflammatory song on commercial for allstateWeb8 nov. 2024 · Lithium was initially used to treat depression, gout, and neutropenia, and for cluster headache prophylaxis, but it fell out of favor because of its adverse effects. The … song on chevrolet commercialWebMIF protects against oxygen-glucose deprivation-induced ototoxicity in HEI-OC1 cochlear cells by enhancement of Akt-Nrf2-HO-1 pathway. Reactive oxygen species MAPK/ERK pathway Pharmacology Downregulation and upregulation Apoptosis Cancer research Ototoxicity. 作者 ... Le Wu, Hong-Hua Li, ... song once the last leaf has fallenWebDOI: 10.1016/j.toxlet.2024.03.010 Corpus ID: 257749274; DJ-1 Protects Auditory Cells from Cisplatin-induced Ototoxicity via Regulating Apoptosis and Autophagy. @article{Wang2024DJ1PA, title={DJ-1 Protects Auditory Cells from Cisplatin-induced Ototoxicity via Regulating Apoptosis and Autophagy.}, author={Yajie Wang and Hao … smallest tracking devices for peopleWebin 1978, Hansen and Amdisen proposed a classification for the severity of lithium intoxication based on serum lithium concentration subdivided their investigational cohort … song on cox commercial 2021WebA randomized controlled trial to test the efficacy of trans-tympanic injections of a sodium thiosulfate gel to prevent cisplatin-induced ototoxicity in patients with head and neck cancer. J Otolaryngol Head Neck Surg . 2024;48(1):4. doi: 10.1186/s40463-019-0327-x PubMed Google Scholar Crossref song on christmas day