Metallothionein 1g
WebArriaga JM, Greco A, Mordoh J and Bianchini M: Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy. Mol Cancer Ther. 13:1369–1381. 2014. View Article: Google Scholar: PubMed/NCBI. 13 Cleveland WS, Devlin SJ and Grosse E: Regression by local fitting: Methods, properties, and computational algorithm. WebDescription: Homo sapiens metallothionein 1G (MT1G), transcript variant 1, mRNA. (from RefSeq NM_005950) Gencode Transcript: ENST00000444837.6 Gencode Gene: ENSG00000125144.14 ... Short=MT-1K; AltName: Full=Metallothionein-IG; Short=MT-IG; FUNCTION: Metallothioneins have a high content of cysteine residues that bind various …
Metallothionein 1g
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Web12 feb. 2024 · Metallothioneins are small cysteine-rich proteins that play important roles in oxidative stress. Metallothionein-1G (MT-1G) is one of functional isoforms in metallothionein-1. Activation of the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is essential for the induction of MT-1G expression after sorafenib treatment. WebMT1Kmetallothionein-1G MT1M MT-IG Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt. Customers Who Viewed This Item Also Viewed... Metallothionein-2A Antibody (6G2) H00004502-M01 • • (3 Publications ) Species: Hu, Mu
WebForest plot of the association between metallothionein expression and overall survival of included studies. ... Kanda M, Nomoto S, Okamura Y, et al. Detection of metallothionein 1G as a methylated tumor suppressor gene in human hepatocellular carcinoma using a novel method of double combination array analysis. Int J Oncol 2009;35:477–83. WebThe activation of p62-Keap1-Nrf2 pathway up-regulates ferritin heavy chain 1 (FTH1), which inhibits ferroptosis in HCC cells by accumulating and transporting Fe2 +. 10 As a negative regulator of ferroptosis, Metallothionein-1G could increase sorafenib resistance of HCC cells and ultimately lead to poor prognosis for patients with HCC. 6 Liang et al built a …
Web1 jan. 2024 · This study aimed to investigate metallothionein (MT)-1G involvement in the regulation of cancer stemness and provide a strategy to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Methods: MT1G was identified as a critical factor related with gemcitabine resistance in PDAC cells by mRNA microarray. Web21 okt. 2016 · Background Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure …
Web1 nov. 2024 · Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma. Lab. Invest. (2008) A. Forner et al. Hepatocellular carcinoma. Lancet (2024) ... Metallothionein 2A (MT2A) controls cell proliferation and liver metastasis by controlling the MST1/LATS2/YAP1 signaling pathway in colorectal cancer.
WebDiagnosis of Wilson disease (WD) can be difficult because of its protean clinical presentations, but early diagnosis is important because effective treatment is available and can prevent disease progression. Similarly, diagnosis of WD on liver biopsy specimens is difficult due to the wide range of histologic appearances. A stain that could help identify … elizabeth mckeen md oncologyWebMetallothioneins (MT) are a family of low molecular weight proteins that are silenced during colorectal cancer progression, mainly through epigenetic mechanisms, and this loss is … elizabeth mckay dresses saleWebMetallothionein 1G functions as a tumor suppressor in thyroid cancer through modulating the PI3K/Akt signaling pathway. GPR56, MT1G, and RASSF1 might be the potential … force in sign languageWeb29 jul. 2014 · A PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiation. We recently revealed that myeloid master regulator … force in science for kidsWeb14 mrt. 2024 · Moreover, sorafenib-induced increase in metallothionein-1G (MT-1G) promoted the resistance of HCC cells to sorafenib . This suggests that secondary resistance to sorafenib and gene expression of HCC cells might affect the therapeutic effect of sorafenib; therefore, mechanisms underlying the resistance to sorafenib need to be … force in scienceWeb[0127]In addition to the sequences provided herein, SERPINE2 oligonucleotide probes, as well as oligonucleotide probes specific for other relevant genes, may be selected from a number of sources including polynucleotide databases such as GenBank, Unigen, HomoloGene, RefSeq, dbEST, and dbSNP. elizabeth mckenna obituaryWeb1 apr. 2024 · Metallothioneins (MT) are the group of low molecular weight, metal binding proteins that are prevalent in many organisms 8. There are 16 isoforms of MTs that are … elizabeth mckenna lcsw