Webdefense againstbacteria.Becausewefoundavery highNox2activityin Slamf8-/-macrophages andDCs(S2Fig.)[10],wetested theROS production bySlamf8 -/- neutrophils.Asjudgedbya lucigenin-basedassay,Slamf8 -/- neutrophils produce indeed significantly moreROS thanwt WebDetects mouse BLAME/SLAMF8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human BLAME is observed. Source Polyclonal Sheep IgG Purification Antigen Affinity-purified Immunogen Mouse myeloma cell line NS0-derived recombinant mouse BLAME/SLAMF8 Val21-Asp231
SLAMF9 regulates pDC homeostasis and function in health
WebJul 25, 2024 · Its role was previously studied during inflammation in a double SLAMF9 and SLAMF8-deficient mice . Therefore, the specific effect of SLAMF9 was not directly … WebSLAMF8 is expressed at low levels on the surface of resting T cells, but the expression of SLAMF8 is significantly upregulated on activated T cells and M1 macrophages. We … divine products online
Cutting Edge: Slamf8 Is a Negative Regulator of Nox2 Activity in ...
WebSLAM family member 8 is a protein that in humans is encoded by the SLAMF8 gene. [5] [6] Function [ edit] This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. WebSLAM, also known as CD150 or SLAMF1, is the founding member of the SLAM family (Cocks et al., 1995). It is expressed on T cells, B cells, activated macrophages, hematopoietic stem cells (HSCs), and platelets. In addition to being a self-ligand (Kd (dissociation constant) = ∼200 μM), SLAM is the lymphocyte-specific receptor for measles virus ... WebAntibodies that detect SLAMF8 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target SLAMF8 in Human, Mouse and Rat samples. Our SLAMF8 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, … divine professional healthcare