Thy-1 promoter
Webb12 juni 2008 · Thy-1 Genomic DNA Is Intact in Human IPF Tissues and Thy-1(−) Fibroblasts; Thy-1 Expression in IPF Tissues and Cultured Fibroblasts Corresponds to the Methylation Status of the Thy-1 Promoter We previously demonstrated that Thy-1 is absent in the FF of IPF and in Thy-1(−) lung fibroblasts and that the absence of Thy-1 … WebbEleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, spinal cord, retina, …
Thy-1 promoter
Did you know?
Webb27 feb. 2024 · Thy-1 deficiency in endothelial cells and its impact on immune cell infiltration. MSCs Thy-1 has long been recognized solely as a marker of MSCs. Friedenstein et al. (65) first described MSCs as ad-herent, spindle-shaped cells isolated from the bone mar-row.Otherthanthebonemarrow,MSCscanalsobefound Webb1 nov. 2015 · The role of TGF-β1 in IPF is discussed, which can affect the fibrotic process of IPF by affecting oxidative stress, epigenetics and other aspects, and most of the processes involved in TGF,β1 promote IPF, but TGF -β1 can also inhibit it. 21 PDF Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis
WebbArticle Snippet: The Thy1-EGFP transgene mice expressing enhanced green fluorescent protein (EGFP) under the control of a modified regulatory region of the mouse thy1.2 … WebbNeuron Specific Mouse Thy1 Promoter, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for … Visa mer The antigen Thy-1 was the first T cell marker to be identified. Thy-1 was discovered by Reif and Allen in 1964 during a search for heterologous antisera against mouse leukemia cells, and was demonstrated by … Visa mer Thy-1 has been conserved throughout vertebrate evolution and even in some invertebrates, with homologs described in many species like squid, frogs, chickens, mice Visa mer Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. … Visa mer As a GPI-anchored protein, Thy-1 is present in the outer leaflet of lipid rafts in the cell membrane. In case of neurons it is known to be expressed strongly in the mature axon. The axon hillock can act as a barrier for its lateral spread even though it has no transmembrane … Visa mer The 25-kDa core protein (excluding the heavy glycosylation) of rodent Thy-1 is 111 or 112 amino acids in length, and is N-glycosylated at three sites (In contrast to only two glycosylation sites for human Thy-1). The 162aa (murine, 161 for human) Thy1 … Visa mer Thy1 expression varies between species. Amongst the cells reported to generally express Thy-1 are thymocytes (precursor of T cells in the thymus) & CD34(+) prothymocytes; neurons, mesenchymal stem cells, hematopoietic stem cells, NK cells, … Visa mer The function of Thy-1 has not yet been fully elucidated. It has speculated roles in cell-cell and cell-matrix interactions, with implication in neurite outgrowth, nerve regeneration, apoptosis, metastasis, inflammation, and fibrosis. Role in cognition Visa mer WebbThy-1 expression is suppressed in lungs of hypoxic mice and this is associated with increased TGFβ1 acti-vation [24]. Whether this suppression was due to in-creased DNA methylation in the Thy-1 promoter was not reported. Given the results from these studies investigating Thy-1 expression and regulation, along with our previous find-
Webb017682 C57BL/6N-Tg(Thy1-SNCA)15Mjff/J This transgenic line expresses human SNCA under the direction of a mouse Thy-1 promoter. Applications exist in studies related to …
WebbContains 6.5 kb of the murine thy1.2 gene, extending from the promoter to the intron following exon 4, but lacking exon 3 and its flanking introns (see Figure 1 in Caroni … dna replication unwindingWebb6 apr. 2024 · We had previously shown that THY1 (CD90) is a tumor suppressor in nasopharyngeal carcinoma (NPC) and that its down-regulation and loss of expression are associated with tumor metastasis, yet the mechanism leading to such effects remains unknown. In this study we show that tumor invasion could be suppressed by THY1 via … create a demand curve graphWebb1 maj 2009 · The Thy-1 promoter has two elements that are traditionally attributed to “housekeeping” genes; specifically it is located within an area of high G/C content and has no classical TATA box [16, 56]. In addition, Thy-1 transcription initiates at multiple sites, and distribution of these sites differs in murine brain and thymus . create a desktop icon for an appdna replication steps detailedWebb15 apr. 2024 · The TAM receptor tyrosine kinases (RTKs) Axl and Mer (gene name Mertk) exert two key functions in macrophages and other immune sentinels 1, 2. First, they are … create a desktop icon for a websiteWebb14 apr. 2010 · On the other hand, the closed chromatin structure marked by H3K27Me3 is associated with transcriptionally repressed Thy-1. The Thy-1 promoter in Thy-1(−) cells demonstrates enrichment by immunoprecipitation of this histone modification, whereas with the TSA treatment, the Thy-1 promoter DNA associated with this protein is reduced . create a derived keyWebbEleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, spinal cord, retina, and dorsal root ganglion. Thy1-Cre expression also resulted in region-specific activation of Cre reporter transgenes. dna replication what phase